1. Design and production of a novel anti-pd-1 nanobody by cdr grafting and site-directed mutagenesis approach

Aleme Mirzaee, Shima Mirhoseini, Mohammad Mehdi Heidari, Mehri Khatami (2025), Molecular biotechnology , 67(), 1843-1851 (No: 33982) (10.1007/s12033-024-01162-1)

2. New strategy for the design and cloning of novel humanized biparatopic anti-cd52 nanobodies: tools for targeted drug delivery and therapeutic approaches

Mohammad Mehdi Heidari, Mehri Khatami, Amir Soltanzade, Soroor Rezaei, Elham sadat Mirhashemi (2025), Biochemical engineering journal , 219(), 109736-1-109736-9 (No: 33983) (10.1016/j.bej.2025.109736)

3. Identification of rare and pathogenic tal2 gene mutations in b-lineage acute lymphoblastic leukemia (b-all) using mutational screening and comprehensive bioinformatics analysis

Fateme Zare khormizi, Hediye Fahandezh saadi, Mehri Khatami, Mohammad Mehdi Heidari, Fateme Tabrizi, Azam Hashemi, Zohre Khanjarpanah (2025), Molecular biology reports , 52(), 52-1-52-16 (No: 33985) (10.1007/s11033-025-10229-4)

5. The comprehensive mutational and bioinformatics analysis reveals novel somatic mutations in the cdkn2a and cdkn2b genes in pediatric patients with b-cell acute lymphoblastic leukemia (b-all)

Mehri Khatami, Farzane Ghasemi, Hamid Saadati, Mohammad Mehdi Heidari, Azam Hashemi, Reyhane Chamani, Zohre Khanjarpanah, Sajede Ghorbani (2025), Cellular, molecular and biomedical reports , 5(4), 226-242 (No: 34502) (10.55705/cmbr.2025.509045.1305)

8. Crispr-cas9-mediated suppression of pd-l1 as a novel strategy in cancer immunotherapy

Melika Doosthosseini, Mohammad Mehdi Heidari, Mehri Khatami, Elham Ramazani (2025), International journal of advanced biological and biomedical research , 14(3), 259-259 (No: 34792) (10.48309/ijabbr.2026.2074847.1671)

9. Novel and deleterious nucleotide variations in the hand1 gene probably affect mirna target sites and protein function in pediatric patients with congenital heart disease

Fateme Tabrizi, Mehri Khatami, Mohammad Mehdi Heidari, José Bragança, Hasan Tatari, Mohsen Namnabat, Mehdi Hadadzadeh, Mohammad Ali Navabi Shirazi (2024), Molecular biology reports , 51(), 468-1-468-14 (No: 31456) (10.1007/s11033-024-09410-y)

10. Cdr grafting and site-directed mutagenesis approach for the generation and affinity maturation of anti-cd20 nanobody

Mohammad Mehdi Heidari, Elham Anbarshirazi, Seyede fatemeh Cheraghi, Roghayeh Shahshahani, TINA RAHNAMA, Mehri Khatami (2024), Molecular biology reports , 51(), 751-1-751-12 (No: 32140) (10.1007/s11033-024-09684-2)

13. Mutational analysis and prediction of the potential impact of missense mutations in the hoxa9 gene in b-cell acute lymphoblastic leukemia

Narges Khamar, Mohammad Mehdi Heidari, Mehri Khatami, Roghayeh Shahshahani (2024), Human gene , 41(), 201318-1-201318-15 (No: 32153) (10.1016/j.humgen.2024.201318)

14. Analysis and identification of rare and prevalent breakpoints in chromosomal rearrangements in adult and pediatric with b-acute lymphoblastic leukemia (b-all): a systematic review

Roghayeh Shahshahani, Mehri Khatami, Mohammad Mehdi Heidari, Parisa sadat Naji esfahani (2024), Iranian journal of pediatric hematology and oncology , 14(3), 227-243 (No: 32169) (10.18502/ijpho.v14i3.15992)

15. Evaluation of the expression of lincoo475 and foxo1 genes as tumor suppressor genes in breast cancer: correlation of bioinformatics tools and experimental approaches

Farzaneh Motamedi, Mehri Khatami, Mohammad Mehdi Heidari, Mansoureh Azadeh, Negar Kararmi (2024), Gene reports , 36(), 101980-1-101980-10 (No: 32170) (10.1016/j.genrep.2024.101980)

18. Novel nucleotide variations in the thrombomodulin (thbd) gene involved in coagulation pathways can increase the risk of recurrent pregnancy loss (rpl)

Mohammad Mehdi Heidari, Bahareh Mazrouei, Maryam Tahmasebi, Fatemeh Bagheri, Zahra Khanjan khani, Mehri Khatami, Mohammadreza Dehghani, Fateme Zare khormizi (2024), Gene , 895(), 148011-1-148011-11 (No: 31455) (10.1016/j.gene.2023.148011)

20. Novel missense mutation in nkx2.6 gene (c.389 g > c, arg130pro) as a potentially pathogenic variant in pediatric patients with congenital heart disease

Mehri Khatami, Donya Ghazi, Fateme Ahmadi, Mohammad Mehdi Heidari, Mehdi Hadadzadeh, Mohsen Namnabat (2023), Gene reports , 33(), 101819-1-101819-10 (No: 29610) (10.1016/j.genrep.2023.101819)

23. Mutational analysis of the vpreb1 gene of pre-bcr complex in a cohort of sporadic pediatric patients with b-cell acute lymphoblastic leukemia

Parisa sadat Naji esfahani, Mehri Khatami, Mohammad Mehdi Heidari, Azam Hashemi, Alireza Jenabzadeh, Reyhane Chamani, Zohre Khanjarpanah (2022), Journal of pediatric hematology oncology , 1(), 1-10 (No: 26940) (10.1097/MPH.0000000000002456)

24. Analysis of missense mutations of cx3cr1 gene in patients with recurrent pregnancy loss using bioinformatics tools

Bahareh Mazrouei, Mohammad Mehdi Heidari, Mehri Khatami (2022), , 30(3), 12-28 (No: 27426)

26. Mutational and bioinformatics analysis of the nkx2.1 gene in a cohort of iranian pediatric patients with congenital hypothyroidism (ch)

Mohammad Mehdi Heidari, Seyed ali Madani manshadi, Ahmadreza Eshghi Banadak sadati, Seyede Fateme Talebi, Mehri Khatami, José Bragança, Mahtab Ordooei, Reyhane Chamani, Farzane Ghasemi (2022), Physiology international , 109(2), 1-17 (No: 27431) (10.1556/2060.2022.00224)

27. Mitochondrial mutations in protein coding genes of respiratory chain including complexes iv, v, and mt-trna genes are associated risk factors for congenital heart disease

Mohammad Mehdi Heidari, Mehri Khatami, Akram Kamalipourravari, Mustafa Kalantari, Mahsa Movahed, Mohammad Hayet Emmamy, Mehdi Hadadzadeh, José Bragança, Mohsen Namnabat, Bahareh Mazrouei (2022), Excli journal , 21(), 1306-1330 (No: 27843) (10.17179/excli2022-5298)

28. A nonsense mutation in mme gene associates with autosomal recessive late-onset charcot- marie- tooth disease

Zeinab Jamiri, Rana Khosravi, Mohammad Mehdi Heidari, Ebrahim Kiani, Javad Gharechahi (2022), Molecular genetics & genomic medicine , 11(2), 1-11 (No: 26898) (10.1002/mgg3.1913)

29. In-silico study to identify the pathogenic single nucleotide polymorphisms in the coding region of cdkn2a gene

Farzane Ghasemi, Mehri Khatami, Mohammad Mehdi Heidari, Reyhane Chamani, Zare-Zardini Hadi (2021), Iranian journal of pediatric hematology and oncology , 11(2), 114-133 (No: 24876) (10.18502/ijpho.v11i2.5844)

30. Mutational screening through comprehensive bioinformatics analysis to detect novel germline mutations in the apc gene in patients with familial adenomatous polyposis (fap)

Faranak Ghadamyari, Mohammad Mehdi Heidari, Sirous Zeinali, Mehri Khatami, Shahin Merat, Hamideh Bagherian, Leili Rejali, Farzane Ghasemi (2021), Journal of clinical laboratory analysis , 35(35), 1-13 (No: 25472) (10.1002/jcla.23768)

31. Novel point mutations in 3-untranslated region of gata4 gene are associated with sporadic non-syndromic atrial and ventricular septal defects

Mehri Khatami, Sajede Ghorbani, MOJGAN REZAEIADERYANI, Sahar Bahaloo, Mehri Azaminaeini, Mohammad Mehdi Heidari, Mehdi Hadadzadeh (2021), Current medical science , 1(), 1-15 (No: 26162) (10.1007/s11596-021-2428-9)

33. Micrornas as a new molecular biomarker for diagnosis and prognosis of t-cell acute lymphoblastic leukemia (t-all): a systematic review

Parisa sadat Naji esfahani, Mohammad Mehdi Heidari, Mehri Khatami, Hadi Zare-Zardini, Reyhane Chamani (2020), Iranian journal of pediatric hematology and oncology , 10(3), 184-199 (No: 22900)

35. Relationship of hypomethylation cpg islands in interleukin-6 gene promoter with il-6 mrna levels in patients with coronary atherosclerosis

Monireh Mohammadpanah, Mohammad Mehdi Heidari, Mehri Khatami, Mehdi Hadadzadeh (2020), Journal of cardiovascular and thoracic research , 12(3), 221-228 (No: 23348) (10.34172/jcvtr.2020.37)

37. Association of pathogenic missense and nonsense mutations in mitochondrial coii gene with familial adenomatous polyposis (fap)

Zahra Shaker ardakani, Mohammad Mehdi Heidari, Mehri Khatami, Morteza Bitaraf Sani (2020), International journal of molecular and cellular medicine , 9(4), 1-11 (No: 23577)

38. Identification of novel missense mutations of the tsh-b subunit gene in pediatric patients with congenital central hypothyroidism

Seyede Fateme Talebi, Mohammad Mehdi Heidari, Mehri Khatami, Mahtab Ordooei (2020), Jentashapir journal of cellular and molecular biology , 11(3), e108948-1-e108948-9 (No: 23578) (10.5812/jjcmb.108948)

39. Polymorphisms of sperm protamine genes and cma3 staining in infertile men with varicocele

Maryam Nayeri, Ali Reza Talebi, Mohammad Mehdi Heidari, Seyed Morteza Seifati, Nasim Tabibnejad (2020), Revista internacional de andrologia , 18(1), 7-13 (No: 22763) (10.1016/j.androl.2018.07.005)

41. Development of one-step tetra-primer arms-pcr for simultaneous detection of the angiotensin converting enzyme (ace) i/d and rs4343 gene polymorphisms and the correlation with cad patients

Mohammad Mehdi Heidari, Mehdi Hadadzadeh , Hossein Fallahzadeh (2019), Avicenna journal of medical biotechnology , 11(1), 118-123 (No: 20601)

42. Protective effect of berberis vulgaris on fenton reaction-induced dna cleavage

Noushin Asadi, Mohammad Mehdi Heidari, Mehri Khatami (2019), Avicenna journal of phytomedicine , 9(3), 213-220 (No: 20602)

44. Detection of novel mitochondrial mutations in cytochrome c oxidase subunit 1 (cox1) in patients with familial adenomatous polyposis (fap)

Elham Afkhami, Mohammad Mehdi Heidari, Mehri Khatami, Faranak Ghadamyari, Sima Dianatpour (2019), Clinical and translational oncology , 1(1), 1-11 (No: 21126) (10.1007/s12094-019-02208-6)

45. Novel point mutations of cited2 gene are associated with non-familial congenital heart disease (chd) in sporadic pediatric patients

Sima Dianatpour, Mehri Khatami, Mohammad Mehdi Heidari, Mehdi Hadadzadeh (2019), Applied biochemistry and biotechnology , 1(), 1-8 (No: 21127) (10.1007/s12010-019-03125-8)

46. Induced pluripotent stem cells (ipscs) based approaches for hematopoietic cancer therapy

Bardia Khandani, Mohammad Mehdi Heidari, Mehri Khatami (2019), Iranian journal of pediatric hematology and oncology , 9(2), 117-130 (No: 20603)

47. Identification of a novel non-sense mutation in tbx5 gene in pediatric patients with congenital heart defects

Mehri Khatami, Mohammad Mehdi Heidari, Fatemeh Kazeminasab, Razieh Zare bidoky (2018), Journal of cardiovascular and thoracic research , 10(1), 41-45 (No: 17635)

48. A novel heteroplasmic mutation in mitochondrial trnaarg gene associated with non-dystrophic myotonias

Mohammad Mehdi Heidari, Abolfazl Keshmirshekan, Mozhgan Bidakhavidi, Azam Khosravi, Zeinab Bandari, Mehri Khatami, Shahriar Nafissi (2018), Acta neurologica belgica , (1), 1-8 (No: 18524) (10.1007/s13760-018-1042-5)

49. Novel point mutations in the nkx2.5 gene in pediatric patients with non-familial congenital heart disease

Mehri Khatami, Mansoure Mazidi, , Mohammad Mehdi Heidari, Mehdi Hadadzadeh (2018), Medicina , 54(), 46-56 (No: 18683) (10.3390/medicina54030046)

50. Novel and heteroplasmic mutations in mitochondrial trna genes in brugada syndrome

MAHSAALSADAT FALLAHTAFTI, Mehri Khatami, Shiva Rezaee, Mohammad Mehdi Heidari, Mehdi Hadadzadeh (2018), Cardiology journal , 25(1), 113-119 (No: 16146) (10.5603/CJ.a2017.0104)

52. Simultaneous genotyping of the rs4762 and rs699 polymor-phisms in angiotensinogen gene and correlation with iranian cad patients with novel hexa-primer arms-pcr

Mehri Khatami, Mohammad Mehdi Heidari, Mehdi Hadadzadeh, Barbara SCHEIBER-MOJDEHKAR, Morteza BITARAF SANI, Massoud Houshmand (2017), Iranian journal of public health , 46(6), 811-819 (No: 15227)

53. Molecular analysis of rs2070744 and rs1799983 polymorphisms of nos3 gene in iranian patients with multiple sclerosis

Mohammad Mehdi Heidari, Mehri Khatami, Yaser Tahamtan (2017), Basic and clinical neuroscience , 4(8), 279-284 (No: 15472)

54. Mutation analysis of the mitochondrial trna genes in iranian coronary atherosclerosis patients

Mohammad Mehdi Heidari, , , Seyed Khalil Frozan-nia (2017), Iranian journal of public health , 46(10), 1379-1385 (No: 15651)

55. Designing and validation of one-step t-arms-pcr for genotyping the enos rs1799983 snp

Mohammad Mehdi Heidari, Mehri Khatami (2017), Iranian journal of biotechnology , 15(3), 208-212 (No: 15652)

57. The association of reninangiotensinogen system genes polymorphisms and idiopathic recurrent pregnancy loss

Mohammad Mehdi Heidari, Mozhgan Sheikholeslami, Mahdiye Yavari, Mehri Khatami, Seyed Mohammad Seyedhassani (2017), Human fertility , 0(0), 1-7 (No: 15782) (10.1080/14647273.2017.1388545)

59. Mutation analysis of the nkx2.5 gene in iranian pediatric patients with congenital hypothyroidism

Mehri Khatami, Mohammad Mehdi Heidari, Fatemeh Tabesh, Mahtab Ordooei, Zohreh Salehifar (2017), Journal of pediatric endocrinology and metabolism , 30(), 1-6 (No: 15470) (10.1515/jpem-2017-0084)

60. A novel nonsense mutation in exon 5 of kind1 gene in an iranian family with kindler syndrome

Mohammad Mehdi Heidari, Mehri Khatami, Kargar saeed, , Hasan Hossein Zadeh, Hamideh Fallah ali abadi (2016), Archives of iranian medicine , 19(6), 403-408 (No: 12144)

61. Upregulation of mir-222 in both helicobacter pylori-infected and noninfected gastric cancer patients

Mina Noormohammad, SADEGHI SAMIRA, TABATABAEIAN HOSSEIN, GHAEDI KAMRAN, TALEBI ARDESHIR , MANSOUREH AZADEH, Mehri Khatami, Mohammad Mehdi Heidari (2016), Journal of genetics , 95(4), 991-995 (No: 12963)

62. Mitochondrial genetic variation in iranian infertile men with varicocele

Mohammad Mehdi Heidari, Mehri Khatami, Amirhossein Danafar, , Ghazaleh Farahmand, Ali Reza Talebi (2016), International journal of fertility and sterility , 10(3), 303-309 (No: 12964)

63. Common rs5918 (pla1/a2) polymorphism in the itgb3 gene and risk of coronary artery disease

Mehri Khatami, Mohammad Mehdi Heidari (2016), Archives of medical science , (1), 9-15 (No: 12158)

64. Polymorphisms in nos3 mthfr apob and tnf-a genes and risk of coronary atherosclerotic lesions in iranian patients

Mohammad Mehdi Heidari, Mehri Khatami, Hadadzade Mehdi, Mahboobe Kazemi, Sahar Mahamed, , (2016), Research in cardiovascular medicine , 5(1), 1-6 (No: 12159)

65. Alkyl chain length effect on construction of copper(ii) complexes with tridentate schiff base ligand and dna interaction

Rasoul Vafazadeh, , Mohammad Mehdi Heidari, Anthony C. Willis (2016), Journal of coordination chemistry , 69(8), 1313-1325 (No: 13030) (10.1080/00958972.2016.1163547)

66. Quantum-dot biosensor for hybridization and detection of r3500q mutation of apolipoprotein b-100 gene

Mohammad Mazloum-Ardakani, , Mohammad Mehdi Heidari (2015), Biosensors and bioelectronics , 72(72), 362-369 (No: 9179)

67. Simple and label-free detection of dna hybridization on a modified graphene nanosheets electrode

Ali Benvidi, , , Mohammad Mazloum-Ardakani, Mohammad Mehdi Heidari, (2015), Talanta , 137(), 80-86 (No: 9247) (10.1016/j.talanta.2015.01.035)

68. Mutation analysis in exons 22 and 24 of scn4a gene in iranian patients with non-dystrophic myotonia

Mohammad Mehdi Heidari, Mehri Khatami, Shahriar Nafissi, , Afshin Khorrami (2015), Iranian journal of neurology , 4(14), 190-194 (No: 9285)

69. Comparison of impedimetric detection of dna hybridization on chemically and electrochemically functionalized multi-wall carbon nanotubes modified electrode

Ali Benvidi, , Mohammad Mazloum-Ardakani, Mohammad Mehdi Heidari (2015), Sensors and actuators b-chemical , 207(), - (No: 3750)

70. Synthesis structure characterization dna binding and cleavage properties of mononuclear and tetranuclear cluster of copper(ii) complexes

Rasoul Vafazadeh, , Mohammad Mehdi Heidari, Anthony C. Willis (2015), Acta chimica slovenica , 62(), 122-129 (No: 9143) (10.17344/acsi.2014.797)

71. Detection of the m268t angiotensinogen a3b2 mutation gene based on screen-printed electrodes modified with a nanocomposite: application to human genomic samples

Mohammad Mazloum-Ardakani, , Mohammad Mehdi Heidari (2015), Microchimica acta , (56), 1-9 (No: 9190) (10.1007/s00604-015-1616-3)

72. The polg polyglutamine tract variants in iranian patients

Mehri Khatami, Mohammad Mehdi Heidari, , (2015), Iranian journal of child neurology , 1(9), 37-41 (No: 9972)

73. Electrochemical detection of the mt-nd6 gene and its enzymatic digestion application in human genomic sample

Mohammad Mazloum-Ardakani, , Mohammad Mehdi Heidari, (2014), Analytical biochemistry , 455(), 60-64 (No: 3753)

74. Simple and label-free electrochemical impedance amelogenin gene hybridization biosensing based on reduced graphene oxide

Ali Benvidi, , Mohammad Mazloum-Ardakani, Mohammad Mehdi Heidari, Ashok Mulchandani (2014), Biosensors and bioelectronics , 58(), 145-152 (No: 3755)

75. The mitochondrial dna mutations associated with cardiac arrhythmia investigated in an lqts family

fatemeh khatami, Mohammad Mehdi Heidari, masoud houshmand (2014), Iranian journal of basic medical sciences , 17(9), 656-661 (No: 4340)

76. Novel point mutations in frataxin gene in iranian patients with friedreich s ataxia

Mohammad Mehdi Heidari, Mehri Khatami, (2014), Iranian journal of child neurology , 8(1), 32-36 (No: 4337)

77. Inheritance examples of algebraic hyperstructures

Bijan Davvaz, Akbar Dehghan Nejad, Mohammad Mehdi Heidari (2013), Information sciences , (224), 180-187 (No: 3748)

78. Sex determination based on amelogenin dna by modified electrode with gold nanoparticle

Mohammad Mazloum-Ardakani, , Ali Benvidi, Mohammad Mehdi Heidari (2013), Analytical biochemistry , 443(), 132-138 (No: 3754)

79. The effect of pomegranate juice as a natural antioxidant to prevent dna damages is detectable by application of electrochemical methods

Mohammad Mazloum-Ardakani, , Mohammad Mehdi Heidari, (2013), Scientia iranica , 20(), 566-570 (No: 3756)

80. Apolipoprotein e gene polymorphism in iranian coronary atherosclerosis patients candidate for coronary artery bypass graft

Mohammad Mehdi Heidari, Seyed Khalil Foruzannia, Mehri Khatami, , (2013), Iranian journal of basic medical sciences , 16(7), 841-844 (No: 4331)

81. Detection of amplified sry gene by a novel electrochemical biosensor based on gold nanoparticles

Mohammad Mazloum-Ardakani, Mohammad Mehdi Heidari, , (2012), Scientia iranica , 19(3), 913-918 (No: 3751)

82. Rapid detection of escherichia coli o157: h7 by fluorescent amplification based specific hybridization (flash) pcr

, Mohammad Mehdi Heidari, Mehri Khatami (2012), Iranian red crescent medical journal , 14(), 595-598 (No: 4481)

83. Digestion of restriction enzyme for the detection of single-base mismatch in dna

Mohammad Mazloum-Ardakani, Mohammad Mehdi Heidari, (2012), Analytical biochemistry , 421(), 125-129 (No: 3752)

84. The polg gene polymorphism in iranian varicocele-associated infertility patients

Mohammad Mehdi Heidari, Mehri Khatami, (2012), Iranian journal of basic medical sciences , 15(2), 739-744 (No: 4341)

85. Increased prevalence 12308 a g mutation in mitochondrial trnaleu (cun) gene associated with earlier age of onset in friedreich ataxia

Mohammad Mehdi Heidari, Mehri Khatami, , Eisa Mahmoudi, (2011), Iranian journal of child neurology , 5(4), 25-31 (No: 4334)

86. Novel missense mitochondrial nd4l gene mutations in friedreich s ataxia

Mohammad Mehdi Heidari, Mehri Khatami (2011), Iranian journal of basic medical sciences , 14(3), 219-224 (No: 4335)